Unique was founded when five families affected by rare chromosome disorders came together to share their stories. Each family contributed to a Little Red Book, passing it along to the next to build a shared narrative of hope, resilience, and connection.

Now, 40 years later, we’ve worked with our incredible members to create a brand-new digital version of the Little Red Book. It’s filled with real-life stories and personal experiences from people around the world living with rare chromosome and gene disorders.

No two stories are the same. With the help of our global community, we’ve gathered powerful insights into life with rare chromosome and gene disorders. Explore the Little Red Book and discover the strength, courage, and uniqueness of our members’ experiences.

Thank you to everyone who has shared their Unique stories with us. We are Unique… and so are you.